Dr. Samar Sheat is a researcher in the Plant Virus Department at the Leibniz Institute-DSMZ, German Collection of Microorganisms and Cell Cultures. Working with a globally diverse collection of cassava virus isolates from South America, Africa, Brazil, and Asia, Dr. Sheat contributes to international efforts to understand and combat cassava viral diseases through innovative diagnostics, resistance discovery, and translational research.
Dr. Sheat’s research focuses on the identification anfresearcgd molecular characterization of viruses causing major cassava diseases, including cassava brown streak disease (CBSD), cassava mosaic disease (CMD) and the discovery of pathogens associated with root rot, witches’ broom, and frog skin diseases. Her work is at the intersection of fundamental and applied plant virology, investigating both the virus and the host plant to understand mechanisms of resistance and susceptibility.
A central focus of her research is to dissect the molecular basis of plant resistance by examining gene function, cellular localization, and protein–protein interactions from both the plant and virus perspectives. Using advanced techniques such as confocal microscopy, transcriptomics, proteomics, and other omics tools, she explores how viral effectors interact with host defense pathways and how resistant cassava lines counteract infection.
Dr. Sheat also leads the high-throughput screening of cassava germplasm to identify sources of natural virus resistance. Her translational research comprises strategies of virus exclusion and elimination to ensure plant health and the evaluation of virus resistance under field conditions. A significant outcome of her work has been the discovery of South American cassava lines with high and broad-spectrum resistance against viruses causing CBSD and the deployment of the material to combat the disease in Eastern and Central Africa. The new material offers vital protection for the crop and secures food security for millions of Africans relying on this cassava for their daily diet. Her ongoing projects aim to broaden the genetic base of resistance, identify novel resistance mechanisms and enhance cassava’s adaptability to diverse environmental challenges.
Dr. Sheat collaborates with global research networks and stakeholders in plant health, contributing to the development of durable virus resistance, improved diagnostic systems, and integrated management strategies for cassava and other tropical crops